Efficient biomarker enrichment with high resolution

Bo Zhang's Group-Advanced Diagnostic Materials Lab

We seek to develop magnetic nanomaterials with innovative surface modification and binding strategy, to achieve highly efficient biomarker enrichment for large volume clinical & environmental samples.

Analytical Chemistry, 2023, 95, 11706.
Bioconjugate Chemistry,2023.
Journal of Chromatography B, 2022, 1119, 123236.
Analyst, 2020, 145, 5685.
Bioinformatics, 2020, 36, 928.
Science (new product), 2019, 364, 696.

Multiplexed biomarker analysis with high sensitivity

Bo Zhang's Group-Advanced Diagnostic Materials Lab

We seek to develop fluorescence enhancing materials and strategies to achieve amplification free, multiplexed biomarker analysis with high sensitivity, and solve related clinical issues including detection of multiple viruses and mutations, various autoimmune markers, panel of cancer markers, etc.

Nature Biomedical Engineering, 2023.
Analytica Chimica Acta, 2023.
Journal of Nanobiotechnology, 2022, 20, 533.
Nature Medicine, 2017, 23, 548.
Nature Medicine, 2014, 20, 948.

Direct visualization of assays for rapid field detection

Bo Zhang's Group-Advanced Diagnostic Materials Lab

With novel fluorescent materials and methods, we seek to achieve equipment free detection of multiple biomarkers, to facilitate point-of-care diagnostics of diseases.

Angew. Chem. Int. Ed., 2024e202318800.