学术成果

2023年

  1. Jiahu Tang, Yiyi Liu, Ruibin Hu, Guanghui Wang, Jiahui Lv, Li Cheng, Tingzhen He, Pan-Lin Shao*, Ying Liu* and Bo Zhang*. "Deciphering ACE2-RBD Binding Affinity through Peptide Scanning: A Molecular Dynamics Simulation Approach" Computers in Biology and Medicine, Under Review.
  2. Jingkai Yang, Ziyi Xu, Le Yu, Bingyun Wang, Ruibin Hu, Jiahu Tang, Hongjun Xiao, Jiahui Lv, Guanghui Wang, Dan Niu, Jia-Xin Li, Ying Liu*, Pan-Lin Shao* and Bo Zhang*. "Novel Class of Organic Fluorophores with Large Stokes Shift for the Visualization of Rapid Protein and Nucleic Acid Assays" Nature Communication, Under Revision.
  3. Hongjun Xiao, Dan Niu, Bo Zhang*. "Combined inhibition of Stat3 and Periostin synergistically protects mice against liver fibrosis"Journal of Hepatology2023,https://doi.org/10.1016/j.jhep.2023.08.034.Full Text
  4. Siyu Zhou, Xiaofeng Fang, Jiahui Lv, Yicheng Yang, Yiqi Zeng, Ying Liu, Weijun Wei, Gang Huang, Bo Zhang* and Changfeng Wu*. "Site-Specific Modification of Single Domain Antibodies by Enzyme-Immobilized Magnetic Beads" Bioconjugate Chemistry34(10), 1914, 2023.Full Text
  5. Ruibin Hu, Yiyi Liu, Guanghui Wang, Jiahui Lv, Jingkai Yang, Hongjun Xiao, Ying Liu, Bo Zhang*. "Amplification-free microRNA profiling with femtomolar sensitivity on a plasmonic enhanced fluorescence nano-chip" Analytica Chimica Acta1280, 341870,2023. Full Text
  6. Ying Liu, Yang Yang, Guanghui Wang, Dou Wang, Pan-Lin Shao, Jiahu Tang, Tingzhen He, Jintao Zheng, Ruibin Hu, Yiyi Liu, Ziyi Xu, Dan Niu, Jiahui Lv, Jingkai Yang, Hongjun Xiao, Shuai Wu, Shuang He, Zhongrong Tang, Yan Liu, Meijie Tang*, Xingyu Jiang*, Jing Yuan*, Hongjie Dai* and Bo Zhang*. "Multiplexed Discrimination of SARS-CoV-2 Variants via Plasmonic-Enhanced Fluorescence in a Portable and Automated Device" Nature Biomedical Engineering, 7, 1636, 2023. Full Text
    Highlighted by 国家自然科学基金委员会.  地址
    Highlighted by 学习强国.  地址
    Highlighted by 南方科技大学新闻.  地址
    Highlighted by iNature.  地址
    Highlighted by 南方科技大学生物医学工程系.  地址
    Highlighted by X-MOL.  地址
    Highlighted by 化学加.  地址
  7. Jiahui Lv, Ying Liu*, Jiahu Tang, Hongjun Xiao, Ruibin Hu, Guanghui Wang, Dan Niu, Pan-Lin Shao, Jingkai Yang, Ziqi Jin, Ziyi Xu, and Bo Zhang*. "A Novel Cell Membrane-Associated RNA Extraction Method and Its Application in the Discovery of Breast Cancer Markers" Analytical Chemistry, 95(31), 11706, 2023. Full Text

2022年

  1. Ruibin Hu, Yang Yang, Ying Liu, Tao Liao, Yiyi Liu, Jiahu Tang, Guanghui Wang, Guoxin Wang, Yongye Liang*, Jing Yuan* and Bo Zhang*. "Multiplexed evaluation of immunity against SARS‑CoV‑2 variants using surface enhanced fluo escence from a nanostructured plasmonic chip" Journal of Nanobiotechnology, 20(1), 533, 2022. Full Text
  2. Ying Liu, Li Cheng, Guanghui Wang, Jiahui Lv, Yifei He, Pan-Lin Shao, Ruibin Hu, Hongjun Xiao, Jiahu Tang, Dan Niu, Jingkai Yang, Zhongrong Tang, Ziyi Xu, Yiyi Liu, Yi Li, Kun Song, Benqing Wu*, Bo Zhang*. "A nano-magnetic size selective cfDNA extraction platform for liquid biopsy with enhanced precision" Journal of Chromatography B, 1119, 123236, 2022. Full Text

2020年及以前

  1. Bo Zhang*, Shuting Zhao, Hao Wan, Ying Liu, Fei Zhang, Xin Guo, Wenqi Zeng, Haiyan Zhang, Linghua Zeng, Jiale Qu, Benqing Wu, Xinhong Wan, Charles R.Cantor, Dongliang Ge*. "High-resolution DNA size enrichment using a magnetic nanoplatform and application in non-invasive prenatal testing" Analyst, 145(17), 5685, 2020. (Cover Art) Full Text
  2. Xin Guo, Bo Zhang, WenqiZeng, Shuting Zhao, Dongliang Ge*. "G3viz: an R package to interactively visualize genetic mutation data using a lollipop-diagram" Bioinformatics, 36(3), 928, 2020. Full Text
  3. Bo Zhang* (1st and Corresponding author), Benjamin A. Pinsky, Jeyarama S. Ananta, Su Zhao, Shylaja Arulkumar, Hao Wan, Malaya K. Sahoo, Janaki Abeynayake, Jesse J. Waggoner, Clay Hopes, Meijie Tang and Hongjie Dai*. "Diagnosis of Zika virus infection on a nanotechnology platform" Nature Medicine, 23, 548, 2017. Full Text
  4. Christelle Pomares*, Bo Zhang* (co-1st and Corresponding author), Shylaja Arulkumar, Geraldine Gonfrier, Pierre Marty, Su Zhao, Steven Cheng, Meijie Tang, Hongjie Dai and Jose Montoya. "Validation of IgG, IgM multiplex plasmonic gold platform in French clinical cohorts for the serodiagnosis and follow-up of Toxoplasma gondii infection" Diagnostic Microbiology and Infectious Disease, 87(3), 213, 2017. Full Text
  5. Xiaohua Chen, Odgerel Oidovsambuu, Ping Liu, Rosslyn Grosely, Menashe Elazar, Virginia D. Winn, Benjamin Fram, Bo Zhang, Hongjie Dai, Bekhbold Dashtseren, Dahgwahdorj Yagaanbuyant, Zulkhuu Genden, Naranbaatar Dashdorj, Andreas Bungert, Naranjargal Dashdorj, Jeffrey S. Glenn*. "A novel quantitative microarray antibody capture (Q‐MAC) assay identifies an extremely high HDV prevalence amongst HBV infected Mongolians" Hepatology, 66(6), 1739, 2017. Full Text
  6. Shoujun Zhu, Qinglai Yang, Alexander Antaris, Jingying Yue, Zhuoran Ma, Huasen Wang, Wei Huang, Hao Wan, Joy Wang, Shuo Diao, Bo Zhang, Xiaoyang Li, Yeteng Zhong, Kuai Yu, Guosong Hong, Jian Luo, Yongye Liang* and Hongjie Dai*. "Molecular imaging of biological systems with a clickable dye in the broad 800- to 1700-nm near infrared window" Proceedings of the National Academy of Sciences, 114(5), 962, 2017. Full Text
  7. Bin Liu, Yaling Li, Hao Wan, Lin Wang, Wei Xu, Shoujun Zhu, Yongye Liang, Bo Zhang, Jiatao Lou*, Hongjie Dai and Kun Qian*. "High performance, multiplexed lung cancer biomarker detection on a plasmonic gold chip" Advanced Functional Materials, 26(44), 7994, 2016. Full Text
  8. Byumseok Koh, Xiaoyang Li, Bo Zhang, Bing Yuan, Yi Lin, Alexander L. Antaris, Hao Wan, Ming Gong, Jiang Yang, Xiaodong Zhang, Yongye Liang and Hongjie Dai*. "Visible to Near-Infrared Fluorescence Enhanced Cellular Imaging on Plasmonic Gold Chips" Small, 12(4), 457, 2016. Full Text
  9. Alexander L. Antaris, Hao Chen, Kai Cheng, Yao Sun, Guosong Hong, Chunrong Qu, Shuo Diao, Zixin Deng, Xianming Hu, Bo Zhang, Xiaodong Zhang, Omar K. Yaghi, Zita R. Alamparambil, Xuechuan Hong*, Zhen Cheng* and Hongjie Dai*. "A small-molecule dye for NIR-II imaging" Nature Materials, 15, 235, 2016. Full Text
  10. Shuo Diao, Jeffrey L. Blackburn, Guosong Hong, Alexander L. Antaris, Junlei Chang, Justin Z. Wu, Bo Zhang, Kai Cheng, Calvin J. Kuo and Hongjie Dai*. "Fluorescence Imaging In Vivo at Wavelengths beyond 1500 nm" Angewandte Chemie International Edition, 54(49), 14758, 2015. Full Text
  11. Valentina Manfe*, Jan Fleckner, Peder Norby Lisby, Bo Zhang, Hongjie Dai and Pernille Keller. "Cytokine detection and simultaneous assessment of rheumatoid factor interference in human serum and synovial fluid using high-sensitivity protein arrays on plasmonic gold chips" BMC Biotechnology, 15, 73, 2015. Full Text
  12. Ju Feng, Ming Gong, Michael J. Kenney, Justin Z. Wu, Bo Zhang, Yanguang Li and Hongjie Dai*. "Nickel-coated silicon photocathode for water splitting in alkaline elextrolytes" Nano Research, 8(5), 1577, 2015. Full Text
  13. Alexander L. Antaris, Omar K. Yaghi, Guosong Hong, Shuo Diao, Bo Zhang, Jiang Yang, Leila Chew and Hongjie Dai*. "Single chirality (6,4) single-walled carbon nanotubes for fluorescence imaging with silicon detectors" Small, 11(47), 6325, 2015. Full Text
  14. Changxin Chen*, Justin Zachary Wu, Kai Tak Lam, Guosong Hong, Ming Gong, Bo Zhang, Yang Lu, Alexander L. Antaris, Shuo Diao, Jing Guo* and Hongjie Dai*. "Graphene Nanoribbons Under Mechanical Strain" Advanced Materials, 27(2), 303, 2015. Full Text
  15. Bo Zhang, Rajiv Kumar, Hongjie Dai* and Brian Feldman*. "A plasmonic Chip for Biomarker Discovery and Diagnosis of Type-1 Diabetes" Nature Medicine, 20, 948, 2014.Full Text
  16. Bo Zhang, Jiang Yang, Yingping Zou, Ming Gong, Hui Chen, Guosong Hong, Alexander L. Antaris, Xiaoyang Li, Chien-Liang Liu, Changxin Chen and Hongjie Dai*. "Plasmonic micro-beads for fluorescence enhanced, multiplexed protein detection with flow cytometry" Chemical Science, 5, 4070, 2014. Full Text
  17. Brian Feldman, Rajiv Kumar, Bo Zhang and Hongjie Dai*. "A novel plasmonic chip for biomarker discovery and point-of-care diagnosis of Type-1 Diabetes" Endocrine Reviews, 35, 3, 2014.
  18. Guosong Hong, Shuo Diao, Junlei Chang, Alexander L. Antaris, Changxin Chen, Bo Zhang, Su Zhao, Dmitriy N. Atochin, Paul L. Huang, Katrin I. Andreasson, Calvin J. Kuo* and Hongjie Dai*. "Through-skull fluorescence imaging of the brain in a new near infrared window" Nature Photonics, 8, 723, 2014. Full Text
  19. Ming Gong, Wu Zhou, Mon-Che Tsai, Jigang Zhou, Mingyun Guan, Meng-Chang Lin, Bo Zhang, Yongfeng Hu, Di-Yan Wang, Jiang Yang, Stephen J. Pennycook, Bing-Joe Hwang and Hongjie Dai*. "Nanoscale nickel oxide/nickel heterostructures for active hydrogen evolution electrocatalysis" Nature Communications, 5, 4695, 2014. Full Text
  20. Guosong Hong, Yingping Zou*, Alexander L. Antaris, Shuo Diao, Di Wu, Kai Cheng, Xiaodong Zhang, Changxin Chen, Bo Liu, Yuehui He, Justin Z. Wu, Jun Yuan, Bo Zhang, Zhimin Tao, Chihiro Fukunaga and Hongjie Dai*. "Ultrafast fluorescence imaging in vivo with conjugated polymer fluorophores in the second near-infrared window" Nature Communications, 5, 4206, 2014. Full Text
  21. Xiaobin Tang, Bo Zhang, Justin A. Jarrell, Jordan V. Price, Hongjie Dai, Paul J. Utz and Sam Strober*. "Ly108 expression distinguishes subsets of invariant NKT cells that help autoantibody production and secrete IL-21 from those that secrete IL-17 in lupus prone NZB/W mice" Journal of Autoimmunity, 50, 87, 2014. Full Text
  22. Ming Gong, Yanguang Li, Hongbo Zhang, Bo Zhang, Wu Zhou, Ju Feng, Hailiang Wang, Yongye Liang, Zhuangjun Fan, Jie Liu and Hongjie Dai*. "Ultrafast high-capacity NiZn battery with NiAlCo-layered double hydroxide" Energy and Environmental Science, 7, 2025, 2014. Full Text
  23. Zhimin Tao, Guosong Hong, Chihiro Shinji, Changxin Chen, Shuo Diao, Alexander L. Antaris, Bo Zhang, Yingping Zou and Hongjie Dai*. "Biological imaging using nanoparticles of small organic molecules with fluorescence at wavelengths longer than 1000 nm" Angewandte Chemie International Edition, 52(49), 13002, 2013. Full Text
  24. Bo Zhang, Justin A. Jarrell, Jordan V. Price, Scott M. Tabakman, Yanguang Li, Ming Gong, Guosong Hong, Ju Feng, Paul J. Utz and Hongjie Dai*. "An integrated peptide antigen microarray on plasmonic gold films for sensitive human antibody profiling" Plos ONE, 8(7), e71043, 2013. Full Text
  25. Yanguang Li, Ming Gong, Yongye Liang, Ju Feng, Ji-Eun Kim, Hailiang Wang, Guosong Hong, Bo Zhang and Hongjie Dai*. "Advanced zinc-air batteries based on high performance hybrid electrocatalysts" Nature Communications, 4, 1805, 2013. Full Text
  26. Bo Zhang, Jordan Price, Guosong Hong, Scott M. Tabakman, Hailiang Wang, Justin A. Jarrell, Ju Feng, Paul J. Utz and Hongjie Dai*. "Multiplexed cytokine detection on plasmonic gold substrates with enhanced near-infrared fluorescence" Nano Research, 6, 113, 2013. Full Text
  27. Ju Feng, Yongye Liang, Hailiang Wang, Yanguang Li, Bo Zhang, Jigang Zhou, Jian Wang, Tom Regier and Hongjie Dai*. "Engineering manganese oxide/nanocarbon hybrid materials for oxygen reduction electrocatalysis" Nano Research, 5 (10), 718, 2012. Full Text
  28. Joshua T. Robinson, Guosong Hong, Yongye Liang, Bo Zhang, Omar K. Yaghi and Hongjie Dai*. "In vivo fluorescence imaging in the second near-infrared window with long circulating carbon nanotubes capable of ultrahigh tumor uptake" Journal of the American Chemical Society, 134 (25), 10664, 2012. Full Text
  29. Guosong Hong, Justin Z. Wu, Joshua T. Robinson, Hailiang Wang, Bo Zhang and Hongjie Dai*. "Three-dimensional imaging of single nanotube molecule endocytosis on plasmonic substrates" Nature Communications, 3, 700, 2012. Full Text
  30. Scott M. Tabakman, Lana Lau, Joshua T. Robinson, Jordan Price, Sarah P. Sherlock, Hailiang Wang, Bo Zhang, Zhuo Chen, Stephanie Tangsombatvisit, Justin A. Jarrell, Paul J. Utz and Hongjie Dai*. "Plasmonic substrates for multiplexed protein microarrays with femtomolar sensitivity and broad dynamic range" Nature Communications, 2, 466, 2011. Full Text
  31. Guosong Hong, Scott M. Tabakman, Kevin Welsher, Zhuo Chen, Joshua T. Robinson, Hailiang Wang, Bo Zhang and Hongjie Dai*. "Near-infrared-fluorescence-enhanced molecular imaging of live cells on gold substrates" Angewante Chemie International Edition, 50(20), 4644, 2011. Full Text
  32. Guo Hong, Bo Zhang, Banghua Peng, Xiaojun Xian, Jin Zhang*, WonMook Choi, Jae-Young Choi*, Jong Min Kim and Zhongfan Liu*. "Direct growth of semiconducting single walled carbon nanotube array" Journal of the American Chemical Society, 131(41), 14642, 2009. Full Text
  33. Bo Zhang, Guo Hong, Banghua Peng, Jin Zhang*, WonMook Choi, Jong Min Kim, Jae-Young Choi* and Zhongfan Liu. "Grow Single-Walled Carbon Nanotubes Cross-Bar in One Batch" The Journal of Physical Chemistry C, 113(14), 5341, 2009. (Cover Art) Full Text

专利成果

  1. 胡瑞彬,张博. 一种二级信号放大的microRNA检测方法和应用. 202311202461.2, 2023/09/18.(已授权)
  2. 吴长锋,张博,周思妤,刘莹,吕嘉晖,曾逸祺,杨毅诚,房晓峰. 功能分子修饰的单域抗体及其制备方法. 202310369285.5, 2023/04/10.
  3. 张博,刘莹,唐梅杰.一种核酸检测芯片、制备方法及核酸检测方法.CN202211160010.2, 2022/09/22.
  4. 张博,杨景凯,徐子屹,邵攀霖,刘莹,胡瑞彬,肖宏军. 一种有机荧光小分子材料、合成方法和应用. CN202210368981.X, 2022/04/08.
  5. Bo Zhang, Hao Wan, Shuting Zhao, Dongliang Ge, Xin Guo. Apparatuses systems and methods using core-shell-shell magnetic beads. WO2021055083A1, 2020/07/10.
  6. 刘莹,张博,宋昆,李毅,邵攀霖,程立,傅暘,杨烽,王光会. 一种核酸的提取方法以及用于核酸提取的试剂盒. CN202110444181.7, 2021/04/23.
  7. Bo Zhang, Shuting Zhao, Hao Wan, Dongliang Ge, Xin Guo, Wenqi Zeng. Apparatuses systems and methods for enrichment and separation of nucleic acids by size. WO2021055084A1, 2020/07/10.
  8. Xin Guo, Dongliang Ge, Bo Zhang. Predicting cancer-related pathogenic impact of somatic mutations using deep learning-based methods. US20200342955A1, 2018/10/29.
  9. Bo Zhang, Dongliang Ge, Xin Guo. Magnetic nanoparticle. WO2019/006293A1, 2018/06/29.
  10. Bo Zhang, Hongjie Dai, Yingping Zou, Ming Gong, Jiang Yang. Plasmonic beads for multiplexed analysis by flow detection systems. WO2015038797A1, 2014/09/11.
  11. Brian Jay Feldman, Hongjie Dai, Rajiv B. Kumar, Bo Zhang. Plasmonic substrate for multiplex assessment of type 1 diabetes. WO2014160175A1, 2014/03/13.
  12. 张博,葛东亮,万昊,赵淑婷,张飞,张海燕. 高磁性微粒径纳米磁珠及其制备方法. CN110038533B, 2020/08/04. (已授权)
  13. 冯传发,万昊,张博,葛东亮,张飞,张海燕,王立军. 一种可以自由升降的加热装置. CN210807683U, 2020/06/19. (已授权)
  14. 冯传发,万昊,张博,葛东亮,张飞,张海燕,王立军. 可灵活更换维护的磁头及其快捷的固定结构. CN210692085U, 2020/06/05. (已授权)
  15. Joshua T. Robinson, Meijie Tang, Su Zhao, Anna Hsu Pao, Hongjie Dai, Bo Zhang, Jeyarama Subramanian Ananta Narayanan. Methods and systems for diagnosis and treatment of viral infections. 11022611, 2021/06/01. (Granted)
  16. Hongjie Dai, Scott M. Tabakman, Guosong Hong, Bo Zhang. Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon. 10088478, 2018/10/02. (Granted)